Students practice using a codon wheel or codon chart to determine the amino acid sequence of DNA and RNA. Worksheet includes a short explanation of transcription, translation, and how amino acids are the building blocks of proteins.

Students practice using the codon chart to determine which amino acids are indicated by the RNA code. They also practice the base pair rule in transcribing DNA to RNA.

This was created to complement a unit on genetics where students may have some difficulty with using codon charts and understanding the central dogma.

I have given students another activity on sickle cell and how a change in the DNA sequence can result in an altered protein. While some students are ready to tackle this concept, others might need some additional help with using codon charts or conceptualizing how amino acids chains are built based on the underlying DNA code.

Grade Level: 9-12
Time Required: 15-20 minutes