Tag: sickle
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Investigation: DNA, Proteins, and Mutations
Explore DNA mutations by transcribing and translating DNA code. Changes in the code result in point mutations, frameshift, and nonsense mutations.
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Reinforcement: DNA, RNA, and Sickle Cell
Students practice DNA and RNA by completing this simple fill-in-the-blank worksheet that focuses on vocabulary related to DNA structure and function.
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Genetics of Blood Disorders – Hemophilia and Sickle Cell
I created this worksheet for anatomy students to practice using Punnett squares and comparing different types of mutations that affect the blood. Ideally, students will have already learned about genetics of blood types. Because I use this worksheet in my anatomy class, I don’t spend a lot of time teaching genetics. However, students do need…
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Genetics of Sickle Cell
This assignment was created for students who miss class and can be completed independently. There are sections to read with questions to answer, focusing on how DNA provides the instructions to make protein. A single base substitution in the gene that codes for hemoglobin results in sickle cell anemia. Students are walked through the process…
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DNA, Proteins, and Sickle Cell
In this activity, students use a codon chart to compare the DNA sequence of HbA (normal hemoglobin) to HbS (sickle cell). The DNA differs in a single base, where the codon for normal hemoglobin codes for glutamine, and the mutant form codes for valine.